How does age effect the inflammatory response?

Age significantly influences the inflammatory response, with both younger and older individuals experiencing distinct patterns. In older adults, the immune system often exhibits a phenomenon known as "inflammaging," characterized by chronic, low-grade inflammation and a diminished ability to respond effectively to infections. Conversely, younger individuals typically have a more robust and adaptive inflammatory response, which can efficiently combat pathogens but may also lead to heightened inflammatory reactions in certain conditions. Overall, aging alters both the intensity and regulation of inflammation, impacting health outcomes.