Can you take Sudafed non drowsy with ibuprofen?

You should not take Excedrin Migraine and ibuprofen together, because Excedrin Migraine (and regular Excedrin Extra Strength) contains Aspirin, which is in the same NSAID category that Ibuprofen is.

Taking them together can increase the risk of damage to the stomach lining, which can cause ulcers.

It is not recommended to even take Ibuprofen with the low-dose aspirin used to prevent heart attack and stroke, because Ibuprofen can wipe out the protective quality you are taking the low-dose aspirin for.

Excedrin Tension Headache contains the Acetaminophen and Caffeine, but not the Aspirin, and this would be safe to take with Ibuprofen.