What are the effects on the body from methanphetamine?

Methamphetamine has severe effects on the body, including increased heart rate, elevated blood pressure, and hyperthermia, which can lead to cardiovascular problems. It also causes significant neurological changes, resulting in anxiety, paranoia, and aggressive behavior. Long-term use can lead to severe dental issues, skin sores, and weight loss due to decreased appetite. Additionally, it can cause lasting damage to the brain's structure and function, impacting memory and emotional regulation.