When selecting a refrigerant for a certain application what qualities would you look for in the refrigerant?

When selecting a refrigerant for a specific application, key qualities to consider include its thermodynamic efficiency, environmental impact (such as global warming potential and ozone depletion potential), safety (toxicity and flammability), and cost-effectiveness. Additionally, the refrigerant's compatibility with system materials and its operating pressure range are important for ensuring reliability and performance. Lastly, regulatory compliance with local and international standards should also be taken into account.