What organelles work with the rough er?

The rough endoplasmic reticulum (ER) primarily collaborates with ribosomes, which are attached to its cytoplasmic surface and are responsible for synthesizing proteins. Once proteins are synthesized, they are often transported to the Golgi apparatus for modification, sorting, and packaging. Additionally, vesicles formed from the rough ER transport these proteins to other organelles or to the cell membrane for secretion.