The search for heretics ordered by the Pope primarily refers to the establishment of the Inquisition, which began in the 12th century. The Inquisition aimed to identify, investigate, and eliminate heretical beliefs that contradicted the teachings of the Catholic Church. This often involved trials, interrogations, and severe punishments for those found guilty of heresy. The most notorious of these efforts occurred during the Spanish Inquisition, which intensified in the late 15th century under King Ferdinand and Queen Isabella.
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