Best and fastest driving route from portland Maine to santa cruz California.?

3,258 mi - about 48 hours driving time

Portland, ME, USA to Santa Cruz, CA, USA
1. Head northwest on Forest Ave toward Cumberland Ave 0.7 mi
2. Take the ramp onto I-295 S
Partial toll road 6.1 mi
3. Merge onto I-95 S
Partial toll road
Passing through New Hampshire
Entering Massachusetts 60.7 mi
4. Take exit 59 to merge onto I-495 S toward Worcester 62.6 mi
5. Take exit 22 for Mass. Pike/I-90
Toll road 0.9 mi
6. Merge onto I-90 W
Toll road
Entering New York 123 mi
7. Continue on NYS Thruway Berkshire Spur
Toll road 6.6 mi
8. Take exit 22-61 for I-87/I-90 toward Buffalo/Albany 0.5 mi
9. Merge onto I-87 N
Toll road 13.6 mi
10. Continue on New York Trwy W (signs for I-90/Buffalo)
Toll road 1.3 mi
11. Merge onto I-90 W
Partial toll road
Passing through Pennsylvania
Entering Ohio 465 mi
12. Take the exit onto I-90 W toward Toledo
Partial toll road 27.7 mi
13. Take the exit onto I-80 W/I-90 W
Partial toll road
Entering Indiana 278 mi
14. Take exit 21 for I-94/IN-51/I-80 0.9 mi
15. Merge onto I-80 W/I-94 W
Continue to follow I-80 W
Partial toll road
Entering Illinois 168 mi
16. Take the exit onto I-80 W toward Davenport
Entering Iowa 193 mi
17. Take the exit onto I-80 W toward Omaha/Council Bluffs
Entering Nebraska 475 mi
18. Take the exit onto I-80 W toward Sidney/Cheyenne
Passing through Wyoming, Utah, Nevada
Entering California 1,232 mi
19. Take the exit onto I-80 W 41.7 mi
20. Take exit 40 to merge onto I-680 S toward Benicia/San Jose 58.3 mi
21. Take exit 12 to merge onto CA-262 S/Mission Blvd toward I-880 1.1 mi
22. Take the ramp onto I-880 S 13.0 mi
23. Continue on CA-17 S 26.5 mi
24. Continue on CA-1 N 1.2 mi
25. Turn right at Mission St 295 ft
26. Take the 1st right onto Highland Ave 0.1 mi
Santa Cruz, CA, USA