During DNA extraction, when the cell wall and cell membrane are ruptured, cellular contents, including DNA, proteins, and other cellular debris, are released into the solution. The DNA, which is long and thread-like, begins to unwind and entangle with itself and other cellular components. This entanglement increases the viscosity of the solution, making it thicker as the concentration of DNA and other macromolecules increases. Additionally, the presence of proteins and polysaccharides can further contribute to the viscous nature of the solution.
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