When a client is receiving a cephalosporin, the nurse must monitor for signs of an allergic reaction, such as rash, itching, or difficulty breathing, especially if the client has a history of penicillin allergy. Additionally, it's important to monitor for gastrointestinal side effects like diarrhea, which can indicate potential antibiotic-associated colitis. Renal function should also be assessed, as cephalosporins can affect kidney function, particularly in patients with pre-existing conditions.
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