Did the Ouran Host Club Series end?

Yes, the "Ouran High School Host Club" series has concluded. The manga, created by Bisco Hatori, ran from 2002 to 2010, with a total of 18 volumes. The anime adaptation aired in 2006 and has not been continued since its initial run. While there have been occasional specials and a live-action series, the main story has officially ended.