Who began the crusade against the use of alcohol?

The crusade against the use of alcohol in the United States was largely spearheaded by the Temperance Movement in the 19th century, with prominent figures like Frances Willard and groups such as the Women's Christian Temperance Union (WCTU) playing key roles. This movement sought to reduce and eventually eliminate alcohol consumption, advocating for public health and moral reform. The efforts culminated in the Prohibition era, which began with the 18th Amendment in 1920.