Why has this Appalachian region not been developed as much as other region?

The Appalachian region has not been developed as much as other areas due to a combination of geographic, economic, and sociopolitical factors. Its rugged terrain and isolation have made infrastructure development challenging and costly. Additionally, the region has historically relied on extractive industries like coal mining, which have faced economic decline and environmental concerns. This has hindered diversification into other sectors, leading to persistent poverty and underinvestment compared to more urbanized regions.