Klinefelter syndrome occurs when a male is born with an extra X chromosome, resulting in a genetic makeup of XXY instead of the typical XY. This chromosomal anomaly typically arises during the formation of sperm or egg cells, where a failure in chromosome separation leads to the extra chromosome. The condition can result in various physical and developmental traits, including reduced testosterone levels and infertility. Klinefelter syndrome is usually diagnosed through genetic testing.
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