Can you take NyQuil if you took Advil Cold and Sinus?

You can check all know interactions of drugs yourself with the website http://www.drugs.com/drug_interactions.php. Simply type in the drugs you wish to find and select the correct drug from the dropdown menu. All known interactions will then appear.

---- Interactions searched:

* acetaminophen (Ingredient of Excedrin) * aspirin (Ingredient of Excedrin) * caffeine (Ingredient of Excedrin) * dextromethorphan (Ingredient of NyQuil Cold/Flu Relief) * doxylamine (Ingredient of NyQuil Cold/Flu Relief) ---- 1 Interaction found:

# aspirin (Ingredient of Excedrin) and caffeine (Ingredient of Excedrin) (Minor Drug-Drug) PROBLEM: One study has reported that coadministration of caffeine and aspirin lead to a 25% increase in the rate of appearance and 17% increase in maximum concentration of salicylate in the plasma. A significantly higher area under the plasma concentration time curve of salicylate was also reported when both drugs were administered together. The exact mechanism of this interaction has not been specified. Physicians and patients should be aware that coadministration of aspirin and caffeine may lead to higher salicylate levels faster.

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