What is the human lethal dose of Oxycontin?

The lethal dose of an opiate varies from person to person depending upon their tolerance.

Oxycontin is a central nervous center depressant. When a person uses this drug it shuts down the nervous system one level at a time. A lethal dosage is reached when the individual's nervous system is depressed to the point that it causes the cessation of respiration and cardiac arrest. Quite plainly the person stops breathing and the heart shuts down resulting in death.

Sleep aids, tranquilizers, and alcohol along with numerous other drugs are also CNS depressant. When Oxycontin is combined with any of these other drugs tolerance is decreased and the amount needed to administer a lethal dose like wise is decreased.

As a general rule of thumb if a person has never taken Oxycontin before, then it is likely that their base line tolerance very low and that even a small dose can mean the difference between life or death. If you are researching this question for any other reason than a purely academic one, take a moment to ponder this. You might as well be asking, "How high of a cliff do I have to jump off of before the fall will actually kill me?" The answer will still be the same. It varies depending on the person, the cliff, the area, and many other factors, but regardless it's probably not a good idea to do it. No second chances.