What did the Indian Removal Act nullify?

The Indian Removal Act of 1830 nullified previous treaties that recognized the sovereign rights of Native American tribes to their ancestral lands in the southeastern United States. It authorized the forced relocation of Native Americans to designated territories west of the Mississippi River, primarily impacting tribes such as the Cherokee, Creek, and Choctaw. This act disregarded tribal autonomy and rights, leading to significant suffering and loss of life during the subsequent forced migrations, most notably the Trail of Tears.