What are major cities on route sixtysix?

Route 66, also known as the "Main Street of America," stretches from Chicago, Illinois, to Santa Monica, California. Major cities along this historic route include St. Louis, Missouri; Tulsa, Oklahoma; Albuquerque, New Mexico; and Flagstaff, Arizona. Each city offers unique attractions and a glimpse into the Americana that defines the Mother Road. The route is celebrated for its rich history and cultural significance.