What are the methods used to isolate and study microsomal fractions in cellular research?

Microsomal fractions in cellular research are isolated using techniques such as differential centrifugation and density gradient centrifugation. These methods involve spinning cell homogenates at different speeds to separate out the microsomes based on their size and density. Once isolated, the microsomal fractions can be studied using various biochemical and molecular techniques to understand their structure and function within the cell.