Francisco Vázquez de Coronado faced several significant challenges during his expedition in the 1540s, including harsh terrain and extreme weather conditions in the southwestern United States. He struggled with supply shortages and the difficulties of managing a diverse group of soldiers and Native American allies, which sometimes led to conflicts. Additionally, Coronado's quest for the fabled Seven Cities of Gold proved elusive, resulting in disillusionment among his men and a lack of the riches he had promised. Ultimately, these obstacles contributed to the expedition's failure to achieve its primary goals.
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