Can you take tramadol and Tylenol at the same time?

It depends. Some forms of tramadol already have acetaminophen in them. It is important that you check to be sure your prescription does not already have acetaminophen in it. If your prescription for tramadol is only tramadol, and you are absolutely certain there is no acetaminophen in it, then yes, they work well together. However if you are in doubt or are not absolutely sure, talk to your doctor or pharmacist first.

Old answer: Yes, if your liver is healthy enough.