What is the frequency of albinism in the population?

Albinism occurs in approximately 1 in 18,000 to 1 in 20,000 individuals in the general population, though its frequency can vary significantly by geographic location and ethnic background. For example, certain regions in Africa may have higher prevalence rates, sometimes as high as 1 in 1,000 in specific populations. This genetic condition results from mutations in one of several genes involved in melanin production, leading to reduced pigmentation in the skin, hair, and eyes.