Under what conditions will a low temperature make a reaction spontaneous apex?

A low temperature can make a reaction spontaneous when it is exothermic, meaning it releases heat, and has a negative change in enthalpy (ΔH < 0). Additionally, if the reaction has a positive change in entropy (ΔS > 0), the Gibbs free energy change (ΔG = ΔH - TΔS) will be negative at low temperatures, favoring spontaneity. Conversely, if the reaction is endothermic (ΔH > 0) and has a negative entropy change (ΔS < 0), it will not be spontaneous at low temperatures.