Determining the proper dose of fentanyl involves assessing the patient's pain severity, opioid tolerance, and overall health status. For opioid-naive patients, initial doses are typically lower to avoid overdose, while those with opioid tolerance may require higher doses. Healthcare providers often start with a transdermal patch or intravenous formulation, adjusting based on the patient's response and any side effects. Regular monitoring and reassessment are crucial to ensure efficacy and safety.
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