Who has the best career touchdown to interception ratio in NFL history?

Through 12 weeks of the 2011 NFL season, for QBs with at least 2000 passing attempts that is Aaron Rodgers of the Green Bay Packers who has 124 career TD passes and 37 career INTs for a 3.35 to 1 TD/INT ratio.

Tom Brady of the New England Patriots is second with 291 career TD passes and 113 career INTs for a 2.58 to 1 TD/INT ratio.