What arcade game has you fight a giant wolf at the end of it and you can play as a ninja and also a woman that fights with a yoyo?

The arcade game you’re referring to is "Ninja Combat." In this game, players can choose to control a ninja or a female fighter who uses a yo-yo as her weapon. The final boss battle features a giant wolf, adding to the game's unique blend of action and fantasy elements. It was released in the early 1990s and is known for its cooperative multiplayer gameplay.