Is adenosine or caffeine more soluble?

Adenosine is generally more soluble in water compared to caffeine. Adenosine is a polar molecule with multiple hydroxyl groups that enhance its solubility. In contrast, caffeine, while also soluble, has a less polar structure due to its methyl groups, making it less soluble than adenosine. Therefore, adenosine has a higher solubility in aqueous solutions than caffeine.