Did any of Victoria and Albert's children have genetic defects?

Yes, several of Queen Victoria and Prince Albert's children had genetic issues, which were largely attributed to the practice of intermarriage among European royalty. Notably, their son Leopold suffered from hemophilia, a genetic disorder that affects blood clotting. Additionally, their daughter Alice's descendants also carried the hemophilia gene, which spread to other royal families in Europe. This pattern highlights the consequences of limited genetic diversity among royal lineages.