Is Vittorio Emanuele II square in Roma Termini zone in Rome Italy safe at night to go with my wife and little daughter?

Hi There, the Termini area is indeed safe for tourists and families. If your hotel is located in that area, I would not worry about safety. If you are considering going to hand out in the evening, that might not be such a great idea - only because there isn't much to do, and you will see many immigrants, etc hanging around in the immediate Piazza Vittorio area. It's not exactly a destination, but is safe for lodging, eating, and very conveniently located close to the train station. This article on the Termini area may be of use to you. http://www.wheninrometours.com/Articles/Around-Rome-and-Italy/The-Skinny-on-Romes-Termini-Station.html