In a 2010 Mercedes-Benz C300, the cigarette lighter fuse is located in the fuse box, which is typically found under the dashboard on the driver's side. To access it, you may need to remove a cover panel. The specific fuse for the cigarette lighter is usually labeled in the fuse diagram, which can be found on the cover or in the owner's manual. Always ensure the vehicle is off before checking or replacing any fuses.
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