Do you need to file a runaway report on your 17 yr old daughter who did not come home from school in South Carolina?

If you'd like her back, you should file either a runaway or missing person's report.

If you have given permission or her to stay elsewhere or you don't really care what happens to her, you could just not bother.

Added: You may also want to take into consideration just how close she is to her 18th birthday. 18 is the age of majority in SC, and after she turns 18 she can, legally speaking, live anywhere she wants.