What is the pKa value of serine and how does it affect its chemical properties?

The pKa value of serine is approximately 13.0. This high pKa value means that serine tends to be deprotonated (lose a hydrogen ion) in aqueous solutions at neutral pH levels. This deprotonation can affect serine's chemical properties by making it more reactive in certain biochemical reactions, such as enzyme-catalyzed processes.