Which law resulted in the removal of native Americans from the eastern portions of the US?

The Indian Removal Act of 1830 resulted in the forced removal of Native Americans from eastern portions of the United States. This law authorized the federal government to negotiate treaties that would require Native tribes to relocate west of the Mississippi River. The most infamous consequence of this policy was the Trail of Tears, where thousands of Native Americans were forcibly displaced, leading to significant suffering and loss of life.