Which sequence accurately describes the testing of medicines for safety?

The testing of medicines for safety typically follows a sequence that begins with preclinical studies, where laboratory and animal testing is conducted to assess toxicity and pharmacological effects. If results are promising, the medicine moves into clinical trials, which are divided into phases: Phase I tests safety in a small group of healthy volunteers, Phase II evaluates efficacy and side effects in a larger patient group, and Phase III further assesses effectiveness and monitors adverse reactions in diverse populations. If successful, the medicine can then be submitted for regulatory approval before it is made available to the public.