What part of the brain does parkinsons effect?

Parkinson's disease primarily affects the basal ganglia, a group of structures in the brain that regulate movement. Specifically, it leads to the degeneration of dopamine-producing neurons in the substantia nigra, a part of the basal ganglia. This loss of dopamine disrupts the balance of signals necessary for smooth and coordinated movements, resulting in the characteristic symptoms of the disease, such as tremors, stiffness, and bradykinesia.