Can you take zzzquil with percocet?

It is not recommended to take ZzzQuil (which contains diphenhydramine) with Percocet (which contains oxycodone and acetaminophen) due to the potential for increased drowsiness, dizziness, and respiratory depression. Both medications can cause central nervous system depression, and combining them can amplify these effects, leading to serious side effects or overdose. It is important to consult with a healthcare provider before combining these medications to ensure safety and effectiveness.