Do colleges look at your middle school grades?

Very competitive colleges will look back as far to your junior high school record. If your school district counted the 6th grade as a part of junior high (as opposed to the last grade of elementary school), then it is possible that your 6th grade grades may be taken into consideration. However, most colleges do not have the time to dig that far back for each applicant, and will only use such grades in rare cases of consideration.