What circulatory system does a chameleon have?

Chameleons possess a closed circulatory system, which is typical of reptiles. This system features a heart with three chambers—two atria and one ventricle—allowing for some mixing of oxygenated and deoxygenated blood. However, the structure of their heart includes a septum that partially separates the two blood types, improving efficiency in oxygen transport. This adaptation supports their active lifestyle and varied metabolic needs.