Once off Prednisone will you go back to how you were before you began taking Prednisone?

Generally, after taking prednisone for a short while, the condition will be resolved. Your appetite will return to normal and you won't be eating everything in sight and retaining water from eating salt. If prednisone is used for long term permanent conditions, then after a while, the effects of your condition will reappear. Depends on the disease, really and also what you mean by going "back to how you were before you began taking prednisone." If you mean, "are there permanent side effects from taking prednisone?" the answer is: long term usage and frequent short term usage of steroids will affect your bones...makes them brittle, but if you are healthy you will rebuild your bone mass. If you have Addison's disease and you go off the medication, you will have a return of symptoms.