How does lift off and launch effect humans?

Lift-off and launch can have significant effects on humans, both physically and psychologically. Physically, the intense acceleration and gravitational forces experienced during launch can lead to G-forces that affect blood flow and bodily functions, potentially causing discomfort or disorientation. Psychologically, the anticipation and excitement of a launch can induce feelings of exhilaration or anxiety, affecting crew performance and wellbeing. Additionally, the experience of space travel can lead to profound changes in perspective and emotional response, often referred to as the "Overview Effect."