Does wolfsbane have any affect on humans?

Wolfsbane is a decorative, but poisonous, perennial herb. It contains Aconitine, which is one of the strongest of plant poisons, first acting as a stimulant but then it paralyzes the nervous system. Doses of 2-5 mg can kill an adult, and children have been known to be poisoned from holding tubers in their hands for a long time.