How much for 2 adults to go from Knoxville TN to columbus ohio?

The cost for two adults to travel from Knoxville, TN, to Columbus, OH, will depend on the mode of transportation. For driving, you can expect fuel costs to be around $50-$70, depending on your vehicle's mileage. If flying, round-trip tickets may range from $200 to $400 per person, so total costs could be between $400 and $800. Additionally, consider accommodation and meal expenses if you plan to stay overnight.