Which histone modification likely leads to chromatin condensation?

Histone modification associated with chromatin condensation is typically the trimethylation of histone H3 at lysine 9 (H3K9me3). This modification is recognized by proteins that promote the formation of heterochromatin, leading to a more compact and transcriptionally inactive chromatin structure. Additionally, H3K27me3 is another modification that can contribute to chromatin compaction and gene silencing.