Most opiate patients are chronic pain patients in formal Pain Management programs, and since Depression is common to all pain patients, PM programs typically require patients to go through some type of mental health therapy. Taking Wellbutrin and other AD's with Fentanyl and other opiates is common, but of course not everyone is the same. For some like me, AD's have the opposite effect, so I can't take them. There are those that do benefit though - the best course is to try it for a short period to see if you're getting any benefit.
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