During the assessment of a patient with a long history of chronic obstructive pulmonary disease (COPD), the nurse is most likely to observe signs such as labored breathing, a persistent cough, and the presence of wheezing or crackles upon auscultation. The patient may also exhibit a barrel chest due to hyperinflation of the lungs, as well as use of accessory muscles for breathing. Additionally, there may be signs of cyanosis or hypoxia, indicating decreased oxygenation.
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