Typically, you should ask them what they want, but that's not always practical. So as a married gay man with children, I suggest you would address it in one of the following ways:
If same last name:
John & Richard Smith & family
John & Richard Smith
Bobby and Susan
The Smith Family
If different last names
John Smith & Richard Jones
Bobby and Susan
Mr. John Smith & Mr. Richard Jones
Bobby and Susan
John Smith & Richard Jones & Family
Notes:
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