yes if it won't hurt what your cleaning. it will mildly irritate the skin but it won't injure you It depends on what you are using it on - to clean concrete or masonry residue. Wet the surface with water first, then apply and brush on. Muriatic acid should be diluted at least 5 to 1. The less dilution the more the vapor will create a breath taking green gas. So stay upwind and wear proper gloves and eye protection. If is is undiluted it will leave a residue that will need to be nuetralized. Copious amounts of water -flushing works, but there are commercially available cleaners at Home Depot, for example that will do a good job.
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