Will five speed trans bolt up to 350 motor in a 1995 s10?

Yes, a five-speed transmission can bolt up to a 350 motor in a 1995 S10, but you will need to ensure that the transmission is compatible with the engine and that proper modifications are made. This may include using an appropriate bell housing, adapter plate, and possibly custom driveshaft lengths. Additionally, you should consider the clutch and hydraulic components for a successful installation. It's advisable to consult specific compatibility guides or forums for detailed information on your setup.