Dimetrodon genus (and specially the Dimetrodon limbatus species) went extinct around 40 My before the appearance of the first dinosaur during the Triassic period of the Mesozoicera.
Spinosaurusgenus appeared only during the Late Jurassic.
There is no possible direct genetic connection between Spinosaurus(a dinosaur therapod) and Dimetrodon (a synapsid mammelian reptil that left no descendents after the «Great Dying», the Permian mass extinction).
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