Several Native American tribes remained east of the Mississippi River, including the Cherokee, Chickasaw, Choctaw, Creek (Muscogee), and Seminole. These tribes primarily inhabited regions in the southeastern United States. They faced significant pressures from European settlers and the U.S. government, leading to forced removals during the 19th century, notably the Trail of Tears. Despite these challenges, many tribes continue to maintain their cultural heritage and presence in the region today.
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