John C. Calhoun argued in support of nullification in response to the 1828 tariff by contending that it unfairly targeted Southern states, imposing economic hardship on them while benefiting Northern industrial interests. He believed that states had the right to nullify Federal Laws that they deemed unconstitutional, as the federal government was a creation of the states. Calhoun asserted that this principle was essential for protecting states' rights and maintaining a balance of power between state and federal authorities. In his view, nullification was a necessary remedy to prevent tyranny and uphold the principles of democracy.
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